33 - The PMDD Myth That Kept Me Sick: Nervous System Regulation, and the Healing Power of Dynamic Range
If you've ever been told to just calm down during PMDD, this episode is for you. Jes Fleming breaks down why nervous system regulation is about more than calming activities, how PMDD affects your stress response and emotional intensity, and why true healing requires dynamic range — not self-suppression.
What You'll Learn in This Episode:
• Why nervous system regulation for PMDD is not the same as being calm all the time
• How PMDD affects stress sensitivity, emotional regulation, and nervous system flexibility in the luteal phase
• The role of allopregnanolone, GABA, cortisol, and autonomic nervous system dysregulation in PMDD
• The difference between suppression and repression — and how unprocessed emotions can worsen PMDD symptoms
• Why calming activities alone may not be enough if your body needs movement, expression, boundaries, or stress-cycle completion
• How to shift from trying to fix yourself into true PMDD healing through Jes's H.E.A.L. framework
• Why symptoms and strong emotions may be communication from the body, not proof that you are broken
Resources Mentioned:
• Her Mood Mentor programs and the H.E.A.L. framework
• Carl Jung: "Wholeness is not achieved by cutting off a portion of one's being, but by integration of the contraries." / "Until you make the unconscious conscious, it will direct your life and you will call it fate."
• Dr. Jill Bolte Taylor's 90-second emotion framework
• Research on PMDD, allopregnanolone, GABA, heart rate variability, cortisol, and stress physiology
Citations Mentioned:
• Hantsoo L, Epperson CN. Allopregnanolone in Premenstrual Dysphoric Disorder (PMDD): Evidence for Dysregulated Sensitivity to GABA-A Receptor Modulating Neuroactive Steroids Across the Menstrual Cycle. Curr Psychiatry Rep. 2020;22(9):45.
• Hantsoo L, Payne JL. Towards understanding the biology of premenstrual dysphoric disorder: From genes to GABA. F1000Research. 2023;12:F1000 Faculty Rev-410.
• Landén M, Wennerblom B, Tygesen H, et al. Heart rate variability in premenstrual dysphoric disorder. Psychoneuroendocrinology. 2004;29(6):733–740.
• Hamidovic A, Davis J, Soumare F, et al. Allopregnanolone Is Associated with a Stress-Induced Reduction of Heart Rate Variability in Premenstrual Dysphoric Disorder. Psychoneuroendocrinology. 2023.
• Hamidovic A, Davis J, Soumare F, et al. Blunted Cortisol Response to Acute Psychosocial Stress in Women With Premenstrual Dysphoric Disorder. Psychoneuroendocrinology. 2024.
• Beddig T, Reinhard I, Kuehner C. Stress, mood, and cortisol during daily life in women with Premenstrual Dysphoric Disorder (PMDD). Psychoneuroendocrinology. 2019;109:104372.
• Bolte Taylor J. Popularized the 90-second emotional wave concept in My Stroke of Insight.
HMM Resources + Services
https://courses.hermoodmentor.com/pmdd-resources
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Listen to the PMDD Pep Talk Podcast
https://courses.hermoodmentor.com/podcasts/pmdd-pep-talk-2
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You can find Jes:
Instagram: @hermoodmentor
Youtube: @hermoodmentor
Website: https://hermoodmentor.com/
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Looking for more support?
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